Cargando…

Can network biology unravel the aetiology of congenital hyperinsulinism?

Congenital Hyperinsulinism is a condition with a number of genetic causes, but for the majority of patients, the underlying aetiology is unknown. We present here a rational argument for the use of computational biology as a valuable resource for identifying new candidate genes which may cause diseas...

Descripción completa

Detalles Bibliográficos
Autores principales:	Stevens, Adam, Cosgrove, Karen E, Padidela, Raja, Skae, Mars S, Clayton, Peter E, Banerjee, Indraneel, Dunne, Mark J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Letter to the Editor
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599136/ https://www.ncbi.nlm.nih.gov/pubmed/23394473 http://dx.doi.org/10.1186/1750-1172-8-21

Ejemplares similares

Feeding Problems Are Persistent in Children with Severe Congenital Hyperinsulinism
por: Banerjee, Indraneel, et al.
Publicado: (2016)

Abnormal Neurodevelopmental Outcomes are Common in Children with Transient Congenital Hyperinsulinism
por: Avatapalle, Hima Bindu, et al.
Publicado: (2013)

Vineland adaptive behavior scales to identify neurodevelopmental problems in children with Congenital Hyperinsulinism (CHI)
por: Salomon-Estebanez, Maria, et al.
Publicado: (2017)

Central venous catheter-associated thrombosis in children with congenital hyperinsulinism
por: Yau, Daphne, et al.
Publicado: (2019)

Atypical Forms of Congenital Hyperinsulinism in Infancy Are Associated With Mosaic Patterns of Immature Islet Cells
por: Han, Bing, et al.
Publicado: (2017)

Enhanced Islet Cell Nucleomegaly Defines Diffuse Congenital Hyperinsulinism in Infancy but Not Other Forms of the Disease
por: Han, Bing, et al.
Publicado: (2016)

Reduced Glycemic Variability in Diazoxide-Responsive Children with Congenital Hyperinsulinism Using Supplemental Omega-3-Polyunsaturated Fatty Acids; A Pilot Trial with MaxEPA(R)
por: Skae, Mars, et al.
Publicado: (2014)

Clinical Diversity in Focal Congenital Hyperinsulinism in Infancy Correlates With Histological Heterogeneity of Islet Cell Lesions
por: Craigie, Ross J., et al.
Publicado: (2018)

Conservatively treated Congenital Hyperinsulinism (CHI) due to K-ATP channel gene mutations: reducing severity over time
por: Salomon-Estebanez, Maria, et al.
Publicado: (2016)

Unravelling the genetic causes of mosaic islet morphology in congenital hyperinsulinism
por: Houghton, Jayne AL, et al.
Publicado: (2019)

In Vitro Recovery of ATP-Sensitive Potassium Channels in β-Cells From Patients With Congenital Hyperinsulinism of Infancy
por: Powell, Philippa D., et al.
Publicado: (2011)

Extreme caution on the use of sirolimus for the congenital hyperinsulinism in infancy patient
por: Banerjee, Indraneel, et al.
Publicado: (2017)

Therapies and outcomes of congenital hyperinsulinism‐induced hypoglycaemia
por: Banerjee, I., et al.
Publicado: (2018)

Somatostatin receptors in congenital hyperinsulinism: Biology to bedside
por: van Albada, Mirjam E., et al.
Publicado: (2022)

Increased proliferation and altered cell cycle regulation in pancreatic stem cells derived from patients with congenital hyperinsulinism
por: Kellaway, Sophie G., et al.
Publicado: (2019)

Correction: Increased proliferation and altered cell cycle regulation in pancreatic stem cells derived from patients with congenital hyperinsulinism
por: Kellaway, Sophie G., et al.
Publicado: (2019)

Insight into hypoglycemia frequency in congenital hyperinsulinism: evaluation of a large UK CGM dataset
por: Worth, Chris, et al.
Publicado: (2022)

Delayed Resolution of Feeding Problems in Patients With Congenital Hyperinsulinism
por: Worth, Chris, et al.
Publicado: (2020)

Efficacy of Dose-Titrated Glucagon Infusions in the Management of Congenital Hyperinsulinism: A Case Series
por: Salomon-Estebanez, Maria, et al.
Publicado: (2020)

Corrigendum: Efficacy of Dose-Titrated Glucagon Infusions in the Management of Congenital Hyperinsulinism: A Case Series
por: Salomon-Estebanez, Maria, et al.
Publicado: (2020)

Altered Phenotype of β-Cells and Other Pancreatic Cell Lineages in Patients With Diffuse Congenital Hyperinsulinism in Infancy Caused by Mutations in the ATP-Sensitive K-Channel
por: Salisbury, Rachel J., et al.
Publicado: (2015)

The burden of congenital hyperinsulinism in the United Kingdom: a cost of illness study
por: Eljamel, Sana, et al.
Publicado: (2018)

Case report: contradictory genetics and imaging in focal congenital hyperinsulinism reinforces the need for pancreatic biopsy
por: Yau, Daphne, et al.
Publicado: (2020)

Variation in Glycemic Outcomes in Focal Forms of Congenital Hyperinsulinism—The UK Perspective
por: Dastamani, Antonia, et al.
Publicado: (2022)

Families’ Experiences of Continuous Glucose Monitoring in the Management of Congenital Hyperinsulinism: A Thematic Analysis
por: Auckburally, Sameera Hannah, et al.
Publicado: (2022)

Congenital hyperinsulinism in infancy and childhood: challenges, unmet needs and the perspective of patients and families
por: Banerjee, Indraneel, et al.
Publicado: (2022)

Endocrinopathies in Aicardi Goutières syndrome—A descriptive case series
por: Worth, Chris, et al.
Publicado: (2020)

Correction to: Congenital hyperinsulinism in infancy and childhood: challenges, unmet needs and the perspective of patients and families
por: Banerjee, Indraneel, et al.
Publicado: (2022)

Familial Focal Congenital Hyperinsulinism
por: Ismail, Dunia, et al.
Publicado: (2011)

The hypoglycaemia error grid: A UK-wide consensus on CGM accuracy assessment in hyperinsulinism
por: Worth, Chris, et al.
Publicado: (2022)

Adjacent mutations in the gating loop of Kir6.2 produce neonatal diabetes and hyperinsulinism
por: Shimomura, Kenju, et al.
Publicado: (2009)

Clustering of Hypoglycemia Events in Patients With Hyperinsulinism: Extension of the Digital Phenotype Through Retrospective Data Analysis
por: Worth, Chris, et al.
Publicado: (2021)

Global Registries in Congenital Hyperinsulinism
por: Pasquini, Tai L. S., et al.
Publicado: (2022)

Syndromic forms of congenital hyperinsulinism
por: Zenker, Martin, et al.
Publicado: (2023)

Congenital Hyperinsulinism International: A Community Focused on Improving the Lives of People Living With Congenital Hyperinsulinism
por: Raskin, Julie, et al.
Publicado: (2022)

Refinement of the critical genomic region for congenital hyperinsulinism in the Chromosome 9p deletion syndrome
por: Banerjee, Indraneel, et al.
Publicado: (2020)

Nifedipine in Congenital Hyperinsulinism- A Case Report
por: Khawash, Papiya, et al.
Publicado: (2015)

Sirolimus treatment of severe congenital hyperinsulinism
por: Amato, Lisa A, et al.
Publicado: (2015)

A Case Series: Congenital Hyperinsulinism
por: Alaei, Mohammad Reza, et al.
Publicado: (2016)

Congenital Hyperinsulinism: Diagnosis and Treatment Update
por: Demirbilek, Hüseyin, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_u0fdvdugc69cl8i754fs5q947f