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Spontaneous rupture of primary splenic angiosarcoma: a case report and literature review

BACKGROUND: Primary angiosarcoma of the spleen is a rare mesenchymal malignant tumor of vascular origin often with a poor prognosis, due to its high metastatic potential. This disease often presents with atraumatic rupture and lethal hemorrhage. CASE PRESENTATION: We report a case of a 65-year-old m...

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Autores principales: Duan, Yun-Fei, Jiang, Yong, Wu, Chuan-Xing, Zhu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599178/
https://www.ncbi.nlm.nih.gov/pubmed/23497454
http://dx.doi.org/10.1186/1477-7819-11-53
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author Duan, Yun-Fei
Jiang, Yong
Wu, Chuan-Xing
Zhu, Feng
author_facet Duan, Yun-Fei
Jiang, Yong
Wu, Chuan-Xing
Zhu, Feng
author_sort Duan, Yun-Fei
collection PubMed
description BACKGROUND: Primary angiosarcoma of the spleen is a rare mesenchymal malignant tumor of vascular origin often with a poor prognosis, due to its high metastatic potential. This disease often presents with atraumatic rupture and lethal hemorrhage. CASE PRESENTATION: We report a case of a 65-year-old man who presented with abdominal pain, anemia, thrombocytopenia, and palpable abdominal mass with unstable blood pressure. Laparotomy revealed a huge actively bleeding spleen, thus splenectomy was performed. Some liver metastasis foci were also found during the procedure. Histopathology diagnosis of the removed spleen was primary splenic angiosarcoma. The patient was discharged on the 10th day post operation with no complication. CONCLUSIONS: Splenic angiosarcoma should be considered one of the differential diagnoses in patients with spleen parenchymal lesions. Definitive diagnosis requires laparotomy followed by splenectomy. In the majority of the patients with spleen angiosarcoma, metastatic diseases have already occurred at the time of laparotomy, so splenectomy is an approach more for diagnostic purpose rather than curative purpose.
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spelling pubmed-35991782013-03-17 Spontaneous rupture of primary splenic angiosarcoma: a case report and literature review Duan, Yun-Fei Jiang, Yong Wu, Chuan-Xing Zhu, Feng World J Surg Oncol Case Report BACKGROUND: Primary angiosarcoma of the spleen is a rare mesenchymal malignant tumor of vascular origin often with a poor prognosis, due to its high metastatic potential. This disease often presents with atraumatic rupture and lethal hemorrhage. CASE PRESENTATION: We report a case of a 65-year-old man who presented with abdominal pain, anemia, thrombocytopenia, and palpable abdominal mass with unstable blood pressure. Laparotomy revealed a huge actively bleeding spleen, thus splenectomy was performed. Some liver metastasis foci were also found during the procedure. Histopathology diagnosis of the removed spleen was primary splenic angiosarcoma. The patient was discharged on the 10th day post operation with no complication. CONCLUSIONS: Splenic angiosarcoma should be considered one of the differential diagnoses in patients with spleen parenchymal lesions. Definitive diagnosis requires laparotomy followed by splenectomy. In the majority of the patients with spleen angiosarcoma, metastatic diseases have already occurred at the time of laparotomy, so splenectomy is an approach more for diagnostic purpose rather than curative purpose. BioMed Central 2013-03-04 /pmc/articles/PMC3599178/ /pubmed/23497454 http://dx.doi.org/10.1186/1477-7819-11-53 Text en Copyright ©2013 Duan et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Duan, Yun-Fei
Jiang, Yong
Wu, Chuan-Xing
Zhu, Feng
Spontaneous rupture of primary splenic angiosarcoma: a case report and literature review
title Spontaneous rupture of primary splenic angiosarcoma: a case report and literature review
title_full Spontaneous rupture of primary splenic angiosarcoma: a case report and literature review
title_fullStr Spontaneous rupture of primary splenic angiosarcoma: a case report and literature review
title_full_unstemmed Spontaneous rupture of primary splenic angiosarcoma: a case report and literature review
title_short Spontaneous rupture of primary splenic angiosarcoma: a case report and literature review
title_sort spontaneous rupture of primary splenic angiosarcoma: a case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599178/
https://www.ncbi.nlm.nih.gov/pubmed/23497454
http://dx.doi.org/10.1186/1477-7819-11-53
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