Exposure of RML scrapie agent to a sodium percarbonate-based product and sodium dodecyl sulfate renders PrP(Sc) protease sensitive but does not eliminate infectivity

BACKGROUND: Prions, the causative agents of the transmissible spongiform encephalopathies, are notoriously difficult to inactivate. Current decontamination recommendations by the World Health Organization include prolonged exposure to 1 N sodium hydroxide or > 20,000 ppm sodium hypochlorite, or a...

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Detalles Bibliográficos
Autores principales: Smith, Jodi D, Nicholson, Eric M, Foster, Gregory H, Greenlee, Justin J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599183/
https://www.ncbi.nlm.nih.gov/pubmed/23311930
http://dx.doi.org/10.1186/1746-6148-9-8

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