Body Surface Area Predicts Plasma Oxaliplatin and Pharmacokinetic Advantage in Hyperthermic Intraoperative Intraperitoneal Chemotherapy

BACKGROUND: Hyperthermic intraoperative intraperitoneal chemotherapy (HIPEC) is used to treat peritoneal surface-spreading malignancies to maximize local drug concentrations while minimizing systemic effects. The pharmacokinetic advantage of HIPEC is defined as the intraperitoneal to intravascular r...

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Detalles Bibliográficos
Autores principales: Leinwand, Joshua C., Bates, Gleneara E., Allendorf, John D., Chabot, John A., Lewin, Sharyn N., Taub, Robert N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2013
Materias:
Gastrointestinal Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599209/
https://www.ncbi.nlm.nih.gov/pubmed/23456384
http://dx.doi.org/10.1245/s10434-012-2790-8

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