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BRAF mutation-specific promoter methylation of FOX genes in colorectal cancer

BACKGROUND: Cancer-specific hypermethylation of (promoter) CpG islands is common during the tumorigenesis of colon cancer. Although associations between certain genetic aberrations, such as BRAF mutation and microsatellite instability, and the CpG island methylator phenotype (CIMP), have been found,...

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Detalles Bibliográficos
Autores principales: van Roon, Eddy H, Boot, Arnoud, Dihal, Ashwin A, Ernst, Robert F, van Wezel, Tom, Morreau, Hans, Boer, Judith M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599401/
https://www.ncbi.nlm.nih.gov/pubmed/23324568
http://dx.doi.org/10.1186/1868-7083-5-2

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