Cargando…

SignaLink 2 – a signaling pathway resource with multi-layered regulatory networks

BACKGROUND: Signaling networks in eukaryotes are made up of upstream and downstream subnetworks. The upstream subnetwork contains the intertwined network of signaling pathways, while the downstream regulatory part contains transcription factors and their binding sites on the DNA as well as microRNAs...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fazekas, Dávid, Koltai, Mihály, Türei, Dénes, Módos, Dezső, Pálfy, Máté, Dúl, Zoltán, Zsákai, Lilian, Szalay-Bekő, Máté, Lenti, Katalin, Farkas, Illés J, Vellai, Tibor, Csermely, Péter, Korcsmáros, Tamás
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Database
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599410/ https://www.ncbi.nlm.nih.gov/pubmed/23331499 http://dx.doi.org/10.1186/1752-0509-7-7

Ejemplares similares

SignaLink3: a multi-layered resource to uncover tissue-specific signaling networks
por: Csabai, Luca, et al.
Publicado: (2021)

Signalogs: Orthology-Based Identification of Novel Signaling Pathway Components in Three Metazoans
por: Korcsmáros, Tamás, et al.
Publicado: (2011)

Targets of drugs are generally, and targets of drugs having side effects are specifically good spreaders of human interactome perturbations
por: Perez-Lopez, Áron R., et al.
Publicado: (2015)

Autophagy Regulatory Network — A systems-level bioinformatics resource for studying the mechanism and regulation of autophagy
por: Türei, Dénes, et al.
Publicado: (2015)

NRF2-ome: An Integrated Web Resource to Discover Protein Interaction and Regulatory Networks of NRF2
por: Türei, Dénes, et al.
Publicado: (2013)

Identification of critical paralog groups with indispensable roles in the regulation of signaling flow
por: Modos, Dezso, et al.
Publicado: (2016)

Neighbours of cancer-related proteins have key influence on pathogenesis and could increase the drug target space for anticancer therapies
por: Módos, Dezső, et al.
Publicado: (2017)

ComPPI: a cellular compartment-specific database for protein–protein interaction network analysis
por: Veres, Daniel V., et al.
Publicado: (2015)

Sherlock: an open-source data platform to store, analyze and integrate Big Data for computational biologists
por: Bohar, Balazs, et al.
Publicado: (2023)

Endosomal crosstalk: meeting points for signaling pathways
por: Pálfy, Máté, et al.
Publicado: (2012)

A systems genomics approach to uncover patient-specific pathogenic pathways and proteins in ulcerative colitis
por: Brooks-Warburton, Johanne, et al.
Publicado: (2022)

The EntOptLayout Cytoscape plug-in for the efficient visualization of major protein complexes in protein–protein interaction and signalling networks
por: Ágg, Bence, et al.
Publicado: (2019)

Learning and Innovative Elements of Strategy Adoption Rules Expand Cooperative Network Topologies
por: Wang, Shijun, et al.
Publicado: (2008)

Starvation-response may not involve Atg1-dependent autophagy induction in non-unikont parasites
por: Földvári-Nagy, László, et al.
Publicado: (2014)

Integrated intra‐ and intercellular signaling knowledge for multicellular omics analysis
por: Türei, Dénes, et al.
Publicado: (2021)

Community Landscapes: An Integrative Approach to Determine Overlapping Network Module Hierarchy, Identify Key Nodes and Predict Network Dynamics
por: Kovács, István A., et al.
Publicado: (2010)

Monte Carlo Simulations of the GE Signa PET/MR for Different Radioisotopes
por: Caribé, Paulo R. R. V., et al.
Publicado: (2020)

Network Biology Approaches to Achieve Precision Medicine in Inflammatory Bowel Disease
por: Thomas, John P, et al.
Publicado: (2021)

Cross-validation study between the HRRT and the PET component of the SIGNA PET/MRI system with focus on neuroimaging
por: Mannheim, Julia G., et al.
Publicado: (2021)

Mapping the epithelial–immune cell interactome upon infection in the gut and the upper airways
por: Poletti, Martina, et al.
Publicado: (2022)

NEMA NU 2–2007 performance characteristics of GE Signa integrated PET/MR for different PET isotopes
por: Caribé, Paulo R. R. V., et al.
Publicado: (2019)

The Emerging Role of Bile Acids in the Pathogenesis of Inflammatory Bowel Disease
por: Thomas, John P., et al.
Publicado: (2022)

Analysing miRNA-Target Gene Networks in Inflammatory Bowel Disease and Other Complex Diseases Using Transcriptomic Data
por: Thomas, John P., et al.
Publicado: (2022)

Linking Proteins to Signaling Pathways for Experiment Design and Evaluation
por: Farkas, Illés J., et al.
Publicado: (2012)

Translocatome: a novel resource for the analysis of protein translocation between cellular organelles
por: Mendik, Péter, et al.
Publicado: (2019)

The ciliary transition zone functions in cell adhesion but is dispensable for axoneme assembly in C. elegans
por: Schouteden, Clementine, et al.
Publicado: (2015)

NDK-1, the Homolog of NM23-H1/H2 Regulates Cell Migration and Apoptotic Engulfment in C. elegans
por: Fancsalszky, Luca, et al.
Publicado: (2014)

Chromatin accessibility established by Pou5f3, Sox19b and Nanog primes genes for activity during zebrafish genome activation
por: Pálfy, Máté, et al.
Publicado: (2020)

The Role of the Plant–Soil Relationship in Agricultural Production—With Particular Regard to PGPB Application and Phytoremediation
por: Kisvarga, Szilvia, et al.
Publicado: (2023)

Perturbation Centrality and Turbine: A Novel Centrality Measure Obtained Using a Versatile Network Dynamics Tool
por: Szalay, Kristóf Z., et al.
Publicado: (2013)

Start2Fold: a database of hydrogen/deuterium exchange data on protein folding and stability
por: Pancsa, Rita, et al.
Publicado: (2016)

SARS-CoV-2 Causes a Different Cytokine Response Compared to Other Cytokine Storm-Causing Respiratory Viruses in Severely Ill Patients
por: Olbei, Marton, et al.
Publicado: (2021)

AmyPro: a database of proteins with validated amyloidogenic regions
por: Varadi, Mihaly, et al.
Publicado: (2018)

Systems-Level Feedbacks of NRF2 Controlling Autophagy upon Oxidative Stress Response
por: Kapuy, Orsolya, et al.
Publicado: (2018)

On the role of bacterial metalloproteases in COVID-19 associated cytokine storm
por: Földvári-Nagy, László, et al.
Publicado: (2021)

Calibration and Improvement of an Odometry Model with Dynamic Wheel and Lateral Dynamics Integration
por: Fazekas, Máté, et al.
Publicado: (2021)

CytokineLink: A Cytokine Communication Map to Analyse Immune Responses—Case Studies in Inflammatory Bowel Disease and COVID-19
por: Olbei, Marton, et al.
Publicado: (2021)

Early administration of remdesivir plus convalescent plasma therapy is effective to treat COVID-19 pneumonia in B-cell depleted patients with hematological malignancies
por: Magyari, Ferenc, et al.
Publicado: (2022)

Extracellular vesicles produced by the human commensal gut bacterium Bacteroides thetaiotaomicron affect host immune pathways in a cell‐type specific manner that are altered in inflammatory bowel disease
por: Gul, Lejla, et al.
Publicado: (2022)

Processive translocation mechanism of the human Bloom’s syndrome helicase along single-stranded DNA
por: Gyimesi, Máté, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_11biqvtbdiqjreu1837bor0mmg