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The 3.5 ångström X−ray structure of the human connexin26 gap junction channel is unlikely that of a fully open channel
The permeability of gap junction channels to metabolites, and not simply to small inorganic ions, is likely to play an important role in development, physiology as well as in etiology of several diseases. Here, we combined dual patch clamp and fluorescence imaging techniques with molecular dynamics...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599431/ https://www.ncbi.nlm.nih.gov/pubmed/23445664 http://dx.doi.org/10.1186/1478-811X-11-15 |