Silencing of STIM1 attenuates hypoxia-induced PASMCs proliferation via inhibition of the SOC/Ca(2+)/NFAT pathway

BACKGROUND: Stromal interaction molecule 1 (STIM1) is a newly discovered Ca(2+) sensor on the endoplasmic reticulum which is an indispensable part in the activation of store-operated Ca(2+) channels (SOC). Recent studies demonstrate that SOC of pulmonary smooth muscle cells (PASMCs) were upregulated...

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Detalles Bibliográficos
Autores principales: Hou, Xianhua, Chen, Jian, Luo, Yongjun, Liu, Fuyu, Xu, Gang, Gao, Yuqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599439/
https://www.ncbi.nlm.nih.gov/pubmed/23289723
http://dx.doi.org/10.1186/1465-9921-14-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599439/
https://www.ncbi.nlm.nih.gov/pubmed/23289723
http://dx.doi.org/10.1186/1465-9921-14-2

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