Dynamics of resistance mutations to NS3 protease inhibitors in a cohort of Brazilian patients chronically infected with hepatitis C virus (genotype 1) treated with pegylated interferon and ribavirin: a prospective longitudinal study

ABSTRACT: About sixty thousand new cases of Hepatitis C virus (HCV) infection are recorded in Brazil each year. These cases are currently treated with pegylated interferon (PEG-IFN) and ribavirin (RBV) with an overall success rate of 50%. New compounds for anti-HCV therapy targeted to the HCV NS3 pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Hoffmann, Luísa, Ramos, Juliene Antonio, de Souza, Elizabeth Valentin, de Araújo Ramos, Ana Lucia, Villela-Nogueira, Cristiane Alves, Ürményi, Turán Péter, Tanuri, Amilcar, Rondinelli, Edson, Silva, Rosane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599441/
https://www.ncbi.nlm.nih.gov/pubmed/23409973
http://dx.doi.org/10.1186/1743-422X-10-57

Ejemplares similares

Ejemplares similares