The role of BRCA1 in homologous recombination repair in response to replication stress: significance in tumorigenesis and cancer therapy

Germ line mutations in breast cancer gene 1 (BRCA1) predispose women to breast and ovarian cancers. Although BRCA1 is involved in many important biological processes, the function of BRCA1 in homologous recombination (HR) mediated repair is considered one of the major mechanisms contributing to its...

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Detalles Bibliográficos
Autor principal: Zhang, Junran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599463/
https://www.ncbi.nlm.nih.gov/pubmed/23388117
http://dx.doi.org/10.1186/2045-3701-3-11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599463/
https://www.ncbi.nlm.nih.gov/pubmed/23388117
http://dx.doi.org/10.1186/2045-3701-3-11

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