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Hepatoma polarization limits CD81 and hepatitis C virus dynamics

Many viruses target the polarized epithelial apex during host invasion. In contrast, hepatitis C virus (HCV) engages receptors at the basal surface of hepatocytes in the polarized liver parenchyma. Hepatocyte polarization limits HCV entry by undefined mechanism(s). Given the recent reports highlight...

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Detalles Bibliográficos
Autores principales: Harris, H J, Clerte, C, Farquhar, M J, Goodall, M, Hu, K, Rassam, P, Dosset, P, Wilson, G K, Balfe, P, IJzendoorn, S C, Milhiet, P E, McKeating, J A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599488/
https://www.ncbi.nlm.nih.gov/pubmed/23126643
http://dx.doi.org/10.1111/cmi.12047