Bivariate segmentation of SNP-array data for allele-specific copy number analysis in tumour samples

BACKGROUND: SNP arrays output two signals that reflect the total genomic copy number (LRR) and the allelic ratio (BAF), which in combination allow the characterisation of allele-specific copy numbers (ASCNs). While methods based on hidden Markov models (HMMs) have been extended from array comparativ...

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Detalles Bibliográficos
Autores principales: Mosén-Ansorena, David, Aransay, Ana María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599505/
https://www.ncbi.nlm.nih.gov/pubmed/23497144
http://dx.doi.org/10.1186/1471-2105-14-84

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599505/
https://www.ncbi.nlm.nih.gov/pubmed/23497144
http://dx.doi.org/10.1186/1471-2105-14-84

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