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The role of 3-ketosteroid 1(2)-dehydrogenase in the pathogenicity of Mycobacterium tuberculosis
BACKGROUND: A growing body of evidence suggests that Mycobacterium tuberculosis (Mtb) uses the host’s cholesterol as a source of carbon and energy during infection. Strains defective in cholesterol transport or degradation exhibit attenuated growth in activated macrophages and diminished infectivity...
Autores principales: | Brzezinska, Marta, Szulc, Izabela, Brzostek, Anna, Klink, Magdalena, Kielbik, Michal, Sulowska, Zofia, Pawelczyk, Jakub, Dziadek, Jaroslaw |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599626/ https://www.ncbi.nlm.nih.gov/pubmed/23425360 http://dx.doi.org/10.1186/1471-2180-13-43 |
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