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MethylPCA: a toolkit to control for confounders in methylome-wide association studies

BACKGROUND: In methylome-wide association studies (MWAS) there are many possible differences between cases and controls (e.g. related to life style, diet, and medication use) that may affect the methylome and produce false positive findings. An effective approach to control for these confounders is...

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Detalles Bibliográficos
Autores principales: Chen, Wenan, Gao, Guimin, Nerella, Srilaxmi, Hultman, Christina M, Magnusson, Patrik KE, Sullivan, Patrick F, Aberg, Karolina A, van den Oord, Edwin JCG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599654/
https://www.ncbi.nlm.nih.gov/pubmed/23452721
http://dx.doi.org/10.1186/1471-2105-14-74