Restoration of klotho gene expression induces apoptosis and autophagy in gastric cancer cells: tumor suppressive role of klotho in gastric cancer

BACKGROUND: The loss of tumor suppressor gene expression is involved in the carcinogenesis of gastric cancer (GC). Klotho is a recently identified tumor suppressor gene that epigenetically inactivated in gastric cancer. However, the signaling pathways involved in the suppressive role of klotho have...

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Detalles Bibliográficos
Autores principales: Xie, Biao, Zhou, Jianping, Shu, Guoshun, Liu, Dong-cai, Zhou, Jiapeng, Chen, Jinhui, Yuan, Lianwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599807/
https://www.ncbi.nlm.nih.gov/pubmed/23432957
http://dx.doi.org/10.1186/1475-2867-13-18

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