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The prospective application of a hypoxic radiosensitizer, doranidazole to rat intracranial glioblastoma with blood brain barrier disruption

BACKGROUND: Glioblastoma is one of the intractable cancers and is highly resistant to ionizing radiation. This radioresistance is partly due to the presence of a hypoxic region which is widely found in advanced malignant gliomas. In the present study, we evaluated the effectiveness of the hypoxic ce...

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Detalles Bibliográficos
Autores principales:	Yasui, Hironobu, Asanuma, Taketoshi, Kino, Junichi, Yamamori, Tohru, Meike, Shunsuke, Nagane, Masaki, Kubota, Nobuo, Kuwabara, Mikinori, Inanami, Osamu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599813/ https://www.ncbi.nlm.nih.gov/pubmed/23496909 http://dx.doi.org/10.1186/1471-2407-13-106

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