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Molecular hydrogen attenuates fatty acid uptake and lipid accumulation through downregulating CD36 expression in HepG2 cells
BACKGROUND: There is accumulating evidence that obesity is closely associated with an impaired free fatty acid metabolism as well as with insulin resistance and inflammation. Excessive fatty acid uptake mediated by fatty acid translocase CD36 plays an important role in hepatic steatosis. Molecular h...
Autores principales: | Iio, Akio, Ito, Mikako, Itoh, Tomohiro, Terazawa, Riyako, Fujita, Yasunori, Nozawa, Yoshinori, Ohsawa, Ikuroh, Ohno, Kinji, Ito, Masafumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599869/ https://www.ncbi.nlm.nih.gov/pubmed/23448206 http://dx.doi.org/10.1186/2045-9912-3-6 |
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