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CALHM1 ion channel mediates purinergic neurotransmission of sweet, bitter and umami tastes

Recognition of sweet, bitter and umami tastes requires the non-vesicular release from taste bud cells of adenosine 5′-triphosphate (ATP), which acts as a neurotransmitter to activate afferent neural gustatory pathways(1). However, how ATP is released to fulfill this function is not fully understood....

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Detalles Bibliográficos
Autores principales:	Taruno, Akiyuki, Vingtdeux, Valérie, Ohmoto, Makoto, Ma, Zhongming, Dvoryanchikov, Gennady, Li, Ang, Adrien, Leslie, Zhao, Haitian, Leung, Sze, Abernethy, Maria, Koppel, Jeremy, Davies, Peter, Civan, Mortimer M., Chaudhari, Nirupa, Matsumoto, Ichiro, Hellekant, Göran, Tordoff, Michael G., Marambaud, Philippe, Foskett, J. Kevin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600154/ https://www.ncbi.nlm.nih.gov/pubmed/23467090 http://dx.doi.org/10.1038/nature11906

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