Postpartum Acquired Hemophilia: A Rare Cause of Postpartum Hemorrhage

A 36-year-old female started having postpartum vaginal bleeding after normal vaginal delivery. She underwent hysterectomy for persistent bleeding and was referred to our institution. An elevation of PTT and normal PT made us suspect postpartum acquired hemophilia (PAH), and it was confirmed by low f...

Descripción completa

Detalles Bibliográficos
Autores principales: Seethala, Srikanth, Gaur, Sumit, Enderton, Elizabeth, Corral, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600239/
https://www.ncbi.nlm.nih.gov/pubmed/23533849
http://dx.doi.org/10.1155/2013/735715
Descripción
Sumario:A 36-year-old female started having postpartum vaginal bleeding after normal vaginal delivery. She underwent hysterectomy for persistent bleeding and was referred to our institution. An elevation of PTT and normal PT made us suspect postpartum acquired hemophilia (PAH), and it was confirmed by low factor VIII activity levels and an elevated factor VIII inhibitor. Hemostasis was achieved with recombinant factor VII concentrates and desmopressin, and factor eradication was achieved with cytoxan, methylprednisolone, and plasmapheresis.

Ejemplares similares