Postpartum Acquired Hemophilia: A Rare Cause of Postpartum Hemorrhage

A 36-year-old female started having postpartum vaginal bleeding after normal vaginal delivery. She underwent hysterectomy for persistent bleeding and was referred to our institution. An elevation of PTT and normal PT made us suspect postpartum acquired hemophilia (PAH), and it was confirmed by low f...

Descripción completa

Detalles Bibliográficos
Autores principales: Seethala, Srikanth, Gaur, Sumit, Enderton, Elizabeth, Corral, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600239/
https://www.ncbi.nlm.nih.gov/pubmed/23533849
http://dx.doi.org/10.1155/2013/735715
_version_ 1782475612317810688
author Seethala, Srikanth
Gaur, Sumit
Enderton, Elizabeth
Corral, Javier
author_facet Seethala, Srikanth
Gaur, Sumit
Enderton, Elizabeth
Corral, Javier
author_sort Seethala, Srikanth
collection PubMed
description A 36-year-old female started having postpartum vaginal bleeding after normal vaginal delivery. She underwent hysterectomy for persistent bleeding and was referred to our institution. An elevation of PTT and normal PT made us suspect postpartum acquired hemophilia (PAH), and it was confirmed by low factor VIII activity levels and an elevated factor VIII inhibitor. Hemostasis was achieved with recombinant factor VII concentrates and desmopressin, and factor eradication was achieved with cytoxan, methylprednisolone, and plasmapheresis.
format Online
Article
Text
id pubmed-3600239
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-36002392013-03-26 Postpartum Acquired Hemophilia: A Rare Cause of Postpartum Hemorrhage Seethala, Srikanth Gaur, Sumit Enderton, Elizabeth Corral, Javier Case Rep Hematol Case Report A 36-year-old female started having postpartum vaginal bleeding after normal vaginal delivery. She underwent hysterectomy for persistent bleeding and was referred to our institution. An elevation of PTT and normal PT made us suspect postpartum acquired hemophilia (PAH), and it was confirmed by low factor VIII activity levels and an elevated factor VIII inhibitor. Hemostasis was achieved with recombinant factor VII concentrates and desmopressin, and factor eradication was achieved with cytoxan, methylprednisolone, and plasmapheresis. Hindawi Publishing Corporation 2013 2013-02-28 /pmc/articles/PMC3600239/ /pubmed/23533849 http://dx.doi.org/10.1155/2013/735715 Text en Copyright © 2013 Srikanth Seethala et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Seethala, Srikanth
Gaur, Sumit
Enderton, Elizabeth
Corral, Javier
Postpartum Acquired Hemophilia: A Rare Cause of Postpartum Hemorrhage
title Postpartum Acquired Hemophilia: A Rare Cause of Postpartum Hemorrhage
title_full Postpartum Acquired Hemophilia: A Rare Cause of Postpartum Hemorrhage
title_fullStr Postpartum Acquired Hemophilia: A Rare Cause of Postpartum Hemorrhage
title_full_unstemmed Postpartum Acquired Hemophilia: A Rare Cause of Postpartum Hemorrhage
title_short Postpartum Acquired Hemophilia: A Rare Cause of Postpartum Hemorrhage
title_sort postpartum acquired hemophilia: a rare cause of postpartum hemorrhage
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600239/
https://www.ncbi.nlm.nih.gov/pubmed/23533849
http://dx.doi.org/10.1155/2013/735715
work_keys_str_mv AT seethalasrikanth postpartumacquiredhemophiliaararecauseofpostpartumhemorrhage
AT gaursumit postpartumacquiredhemophiliaararecauseofpostpartumhemorrhage
AT endertonelizabeth postpartumacquiredhemophiliaararecauseofpostpartumhemorrhage
AT corraljavier postpartumacquiredhemophiliaararecauseofpostpartumhemorrhage

Ejemplares similares