Cargando…

Hepatic Epithelioid Hemangioendothelioma and the Danger of Misdiagnosis: Report of a Case

Malignant hepatic epithelioid hemangioendothelioma (HEHE) is a rare malignant tumor of vascular origin. Nonspecific symptoms and the absence of experience of surgeons, radiologists, and histopathologists due to the rarity of HEHE make the diagnosis of this entity very challenging. Misdiagnosis is no...

Descripción completa

Detalles Bibliográficos
Autores principales: Neofytou, Kyriakos, Chrysochos, Andreas, Charalambous, Nikolas, Dietis, Menelaos, Petridis, Christos, Andreou, Charalampos, Petrou, Athanasios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600255/
https://www.ncbi.nlm.nih.gov/pubmed/23533870
http://dx.doi.org/10.1155/2013/243939
_version_ 1782475615747702784
author Neofytou, Kyriakos
Chrysochos, Andreas
Charalambous, Nikolas
Dietis, Menelaos
Petridis, Christos
Andreou, Charalampos
Petrou, Athanasios
author_facet Neofytou, Kyriakos
Chrysochos, Andreas
Charalambous, Nikolas
Dietis, Menelaos
Petridis, Christos
Andreou, Charalampos
Petrou, Athanasios
author_sort Neofytou, Kyriakos
collection PubMed
description Malignant hepatic epithelioid hemangioendothelioma (HEHE) is a rare malignant tumor of vascular origin. Nonspecific symptoms and the absence of experience of surgeons, radiologists, and histopathologists due to the rarity of HEHE make the diagnosis of this entity very challenging. Misdiagnosis is not a rare event, and the consequences of such an event are catastrophic. We report a case of a patient suffering from HEHE in which the initial diagnosis was hepatocellular carcinoma (HCC). The presence of normal laboratory values, liver function tests, tumor markers along with the absence of a chronic liver disease, or any other predisposing factors for HCC, was in contrast with the diagnosis of HCC. Clinical suspicion drove us to the repetition of a liver biopsy and the reevaluation of the sample by a more experience histopathology department in liver tumors. The last biopsy confirmed the diagnosis of HEHE, and the patient escaped any unnecessary treatment for a nonexisting HCC.
format Online
Article
Text
id pubmed-3600255
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-36002552013-03-26 Hepatic Epithelioid Hemangioendothelioma and the Danger of Misdiagnosis: Report of a Case Neofytou, Kyriakos Chrysochos, Andreas Charalambous, Nikolas Dietis, Menelaos Petridis, Christos Andreou, Charalampos Petrou, Athanasios Case Rep Oncol Med Case Report Malignant hepatic epithelioid hemangioendothelioma (HEHE) is a rare malignant tumor of vascular origin. Nonspecific symptoms and the absence of experience of surgeons, radiologists, and histopathologists due to the rarity of HEHE make the diagnosis of this entity very challenging. Misdiagnosis is not a rare event, and the consequences of such an event are catastrophic. We report a case of a patient suffering from HEHE in which the initial diagnosis was hepatocellular carcinoma (HCC). The presence of normal laboratory values, liver function tests, tumor markers along with the absence of a chronic liver disease, or any other predisposing factors for HCC, was in contrast with the diagnosis of HCC. Clinical suspicion drove us to the repetition of a liver biopsy and the reevaluation of the sample by a more experience histopathology department in liver tumors. The last biopsy confirmed the diagnosis of HEHE, and the patient escaped any unnecessary treatment for a nonexisting HCC. Hindawi Publishing Corporation 2013 2013-02-28 /pmc/articles/PMC3600255/ /pubmed/23533870 http://dx.doi.org/10.1155/2013/243939 Text en Copyright © 2013 Kyriakos Neofytou et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Neofytou, Kyriakos
Chrysochos, Andreas
Charalambous, Nikolas
Dietis, Menelaos
Petridis, Christos
Andreou, Charalampos
Petrou, Athanasios
Hepatic Epithelioid Hemangioendothelioma and the Danger of Misdiagnosis: Report of a Case
title Hepatic Epithelioid Hemangioendothelioma and the Danger of Misdiagnosis: Report of a Case
title_full Hepatic Epithelioid Hemangioendothelioma and the Danger of Misdiagnosis: Report of a Case
title_fullStr Hepatic Epithelioid Hemangioendothelioma and the Danger of Misdiagnosis: Report of a Case
title_full_unstemmed Hepatic Epithelioid Hemangioendothelioma and the Danger of Misdiagnosis: Report of a Case
title_short Hepatic Epithelioid Hemangioendothelioma and the Danger of Misdiagnosis: Report of a Case
title_sort hepatic epithelioid hemangioendothelioma and the danger of misdiagnosis: report of a case
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600255/
https://www.ncbi.nlm.nih.gov/pubmed/23533870
http://dx.doi.org/10.1155/2013/243939
work_keys_str_mv AT neofytoukyriakos hepaticepithelioidhemangioendotheliomaandthedangerofmisdiagnosisreportofacase
AT chrysochosandreas hepaticepithelioidhemangioendotheliomaandthedangerofmisdiagnosisreportofacase
AT charalambousnikolas hepaticepithelioidhemangioendotheliomaandthedangerofmisdiagnosisreportofacase
AT dietismenelaos hepaticepithelioidhemangioendotheliomaandthedangerofmisdiagnosisreportofacase
AT petridischristos hepaticepithelioidhemangioendotheliomaandthedangerofmisdiagnosisreportofacase
AT andreoucharalampos hepaticepithelioidhemangioendotheliomaandthedangerofmisdiagnosisreportofacase
AT petrouathanasios hepaticepithelioidhemangioendotheliomaandthedangerofmisdiagnosisreportofacase