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Hepatic Epithelioid Hemangioendothelioma and the Danger of Misdiagnosis: Report of a Case
Malignant hepatic epithelioid hemangioendothelioma (HEHE) is a rare malignant tumor of vascular origin. Nonspecific symptoms and the absence of experience of surgeons, radiologists, and histopathologists due to the rarity of HEHE make the diagnosis of this entity very challenging. Misdiagnosis is no...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600255/ https://www.ncbi.nlm.nih.gov/pubmed/23533870 http://dx.doi.org/10.1155/2013/243939 |
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author | Neofytou, Kyriakos Chrysochos, Andreas Charalambous, Nikolas Dietis, Menelaos Petridis, Christos Andreou, Charalampos Petrou, Athanasios |
author_facet | Neofytou, Kyriakos Chrysochos, Andreas Charalambous, Nikolas Dietis, Menelaos Petridis, Christos Andreou, Charalampos Petrou, Athanasios |
author_sort | Neofytou, Kyriakos |
collection | PubMed |
description | Malignant hepatic epithelioid hemangioendothelioma (HEHE) is a rare malignant tumor of vascular origin. Nonspecific symptoms and the absence of experience of surgeons, radiologists, and histopathologists due to the rarity of HEHE make the diagnosis of this entity very challenging. Misdiagnosis is not a rare event, and the consequences of such an event are catastrophic. We report a case of a patient suffering from HEHE in which the initial diagnosis was hepatocellular carcinoma (HCC). The presence of normal laboratory values, liver function tests, tumor markers along with the absence of a chronic liver disease, or any other predisposing factors for HCC, was in contrast with the diagnosis of HCC. Clinical suspicion drove us to the repetition of a liver biopsy and the reevaluation of the sample by a more experience histopathology department in liver tumors. The last biopsy confirmed the diagnosis of HEHE, and the patient escaped any unnecessary treatment for a nonexisting HCC. |
format | Online Article Text |
id | pubmed-3600255 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-36002552013-03-26 Hepatic Epithelioid Hemangioendothelioma and the Danger of Misdiagnosis: Report of a Case Neofytou, Kyriakos Chrysochos, Andreas Charalambous, Nikolas Dietis, Menelaos Petridis, Christos Andreou, Charalampos Petrou, Athanasios Case Rep Oncol Med Case Report Malignant hepatic epithelioid hemangioendothelioma (HEHE) is a rare malignant tumor of vascular origin. Nonspecific symptoms and the absence of experience of surgeons, radiologists, and histopathologists due to the rarity of HEHE make the diagnosis of this entity very challenging. Misdiagnosis is not a rare event, and the consequences of such an event are catastrophic. We report a case of a patient suffering from HEHE in which the initial diagnosis was hepatocellular carcinoma (HCC). The presence of normal laboratory values, liver function tests, tumor markers along with the absence of a chronic liver disease, or any other predisposing factors for HCC, was in contrast with the diagnosis of HCC. Clinical suspicion drove us to the repetition of a liver biopsy and the reevaluation of the sample by a more experience histopathology department in liver tumors. The last biopsy confirmed the diagnosis of HEHE, and the patient escaped any unnecessary treatment for a nonexisting HCC. Hindawi Publishing Corporation 2013 2013-02-28 /pmc/articles/PMC3600255/ /pubmed/23533870 http://dx.doi.org/10.1155/2013/243939 Text en Copyright © 2013 Kyriakos Neofytou et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Neofytou, Kyriakos Chrysochos, Andreas Charalambous, Nikolas Dietis, Menelaos Petridis, Christos Andreou, Charalampos Petrou, Athanasios Hepatic Epithelioid Hemangioendothelioma and the Danger of Misdiagnosis: Report of a Case |
title | Hepatic Epithelioid Hemangioendothelioma and the Danger of Misdiagnosis: Report of a Case |
title_full | Hepatic Epithelioid Hemangioendothelioma and the Danger of Misdiagnosis: Report of a Case |
title_fullStr | Hepatic Epithelioid Hemangioendothelioma and the Danger of Misdiagnosis: Report of a Case |
title_full_unstemmed | Hepatic Epithelioid Hemangioendothelioma and the Danger of Misdiagnosis: Report of a Case |
title_short | Hepatic Epithelioid Hemangioendothelioma and the Danger of Misdiagnosis: Report of a Case |
title_sort | hepatic epithelioid hemangioendothelioma and the danger of misdiagnosis: report of a case |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600255/ https://www.ncbi.nlm.nih.gov/pubmed/23533870 http://dx.doi.org/10.1155/2013/243939 |
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