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Inhibitors of Fatty Acid Synthesis Induce PPARα-Regulated Fatty Acid β-Oxidative Genes: Synergistic Roles of L-FABP and Glucose

While TOFA (acetyl CoA carboxylase inhibitor) and C75 (fatty acid synthase inhibitor) prevent lipid accumulation by inhibiting fatty acid synthesis, the mechanism of action is not simply accounted for by inhibition of the enzymes alone. Liver fatty acid binding protein (L-FABP), a mediator of long c...

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Detalles Bibliográficos
Autores principales:	Huang, Huan, McIntosh, Avery L., Martin, Gregory G., Petrescu, Anca D., Landrock, Kerstin K., Landrock, Danilo, Kier, Ann B., Schroeder, Friedhelm
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600304/ https://www.ncbi.nlm.nih.gov/pubmed/23533380 http://dx.doi.org/10.1155/2013/865604

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