Activation of epidermal toll-like receptor 2 enhances tight junction function – Implications for atopic dermatitis and skin barrier repair

Atopic dermatitis (AD) is characterized by epidermal tight junction (TJ) defects and a propensity for Staphylococcus aureus (S. aureus) skin infections. S. aureus is sensed by many pattern recognition receptors including toll-like receptor (TLR) 2. We hypothesized that an effective innate immune res...

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Detalles Bibliográficos
Autores principales: Kuo, I-Hsin, Carpenter-Mendini, Amanda, Yoshida, Takeshi, McGirt, Laura Y., Ivanov, Andrei I., Barnes, Kathleen C., Gallo, Richard L., Borkowski, Andrew W., Yamasaki, Kenshi, Leung, Donald Y., Georas, Steve N., De Benedetto, Anna, Beck, Lisa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600383/
https://www.ncbi.nlm.nih.gov/pubmed/23223142
http://dx.doi.org/10.1038/jid.2012.437

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