The synthetic triterpenoid, RTA405, increases glomerular filtration rate and reduces angiotensin II-induced contraction of glomerular mesangial cells

Bardoxolone methyl, a synthetic triterpenoid, improves the estimated glomerular filtration rate (GFR) in patients with chornic kidney disease and type 2 diabetes. Since the contractile activity of mesangial cells may influence glomerular filtration, we evaluated the effect of the synthetic triterpen...

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Detalles Bibliográficos
Autores principales: Ding, Yanfeng, Stidham, Rhesa, Bumeister, Ron, Trevino, Isaac, Winters, Ali, Sprouse, Marc, Ding, Min, Ferguson, Deborah A., Meyer, Colin J., Wigley, W. Christian, Ma, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600401/
https://www.ncbi.nlm.nih.gov/pubmed/23235569
http://dx.doi.org/10.1038/ki.2012.393

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