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Development of a cost-effective high-throughput process of microsatellite analysis involving miniaturized multiplexed PCR amplification and automated allele identification

BACKGROUND: Microsatellites are nucleotide sequences of tandem repeats occurring throughout the genome, which have been widely used in genetic linkage analysis, studies of loss of heterozygosity, determination of lineage and clonality, and the measurement of genome instability or the emergence of dr...

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Detalles Bibliográficos
Autores principales: Nguyen, Truc TM, Lakhan, Shaheen E, Finette, Barry A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600708/
https://www.ncbi.nlm.nih.gov/pubmed/23496942
http://dx.doi.org/10.1186/1479-7364-7-6