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Comparisons of Analysis Methods for Proof-of-Concept Trials

Drug development struggles with high costs and time consuming processes. Hence, a need for new strategies has been accentuated by many stakeholders in drug development. This study proposes the use of pharmacometric models to rationalize drug development. Two simulated examples, within the therapeuti...

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Detalles Bibliográficos
Autores principales: Karlsson, K E, Vong, C, Bergstrand, M, Jonsson, E N, Karlsson, M O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600728/
https://www.ncbi.nlm.nih.gov/pubmed/23887593
http://dx.doi.org/10.1038/psp.2012.24