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Comparisons of Analysis Methods for Proof-of-Concept Trials
Drug development struggles with high costs and time consuming processes. Hence, a need for new strategies has been accentuated by many stakeholders in drug development. This study proposes the use of pharmacometric models to rationalize drug development. Two simulated examples, within the therapeuti...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600728/ https://www.ncbi.nlm.nih.gov/pubmed/23887593 http://dx.doi.org/10.1038/psp.2012.24 |