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Evolutionary Stability of a Refactored Phage Genome
[Image: see text] Engineered genetic systems are commonly unstable; if propagated, they evolve to reverse or modify engineered elements because the elements impair fitness. A goal of synthetic biology is thus to anticipate and avoid detrimental engineering, but little is yet known about which types...
Autores principales: | Springman, Rachael, Molineux, Ian J., Duong, Chanan, Bull, Robert J., Bull, James J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2012
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600784/ https://www.ncbi.nlm.nih.gov/pubmed/23519680 http://dx.doi.org/10.1021/sb300040v |
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