Deficiency for endoglin in tumor vasculature weakens the endothelial barrier to metastatic dissemination

Therapy-induced resistance remains a significant hurdle to achieve long-lasting responses and cures in cancer patients. We investigated the long-term consequences of genetically impaired angiogenesis by engineering multiple tumor models deprived of endoglin, a co-receptor for TGF-β in endothelial ce...

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Detalles Bibliográficos
Autores principales: Anderberg, Charlotte, Cunha, Sara I., Zhai, Zhenhua, Cortez, Eliane, Pardali, Evangelia, Johnson, Jill R., Franco, Marcela, Páez-Ribes, Marta, Cordiner, Ross, Fuxe, Jonas, Johansson, Bengt R., Goumans, Marie-José, Casanovas, Oriol, ten Dijke, Peter, Arthur, Helen M., Pietras, Kristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600899/
https://www.ncbi.nlm.nih.gov/pubmed/23401487
http://dx.doi.org/10.1084/jem.20120662

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600899/
https://www.ncbi.nlm.nih.gov/pubmed/23401487
http://dx.doi.org/10.1084/jem.20120662

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