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IL-27 inhibits HIV-1 infection in human macrophages by down-regulating host factor SPTBN1 during monocyte to macrophage differentiation

The susceptibility of macrophages to HIV-1 infection is modulated during monocyte differentiation. IL-27 is an anti-HIV cytokine that also modulates monocyte activation. In this study, we present new evidence that IL-27 promotes monocyte differentiation into macrophages that are nonpermissive for HI...

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Detalles Bibliográficos
Autores principales:	Dai, Lue, Lidie, Kristy B., Chen, Qian, Adelsberger, Joseph W., Zheng, Xin, Huang, DaWei, Yang, Jun, Lempicki, Richard A., Rehman, Tauseef, Dewar, Robin L., Wang, Yanmei, Hornung, Ronald L., Canizales, Kelsey A., Lockett, Stephen J., Lane, H. Clifford, Imamichi, Tomozumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600911/ https://www.ncbi.nlm.nih.gov/pubmed/23460728 http://dx.doi.org/10.1084/jem.20120572

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