Blood-brain barrier transport of amyloid beta peptides in efflux pump knock-out animals evaluated by in vivo optical imaging

BACKGROUND: Aβ transport (flux) across the blood-brain barrier (BBB) is thought to contribute to the pathogenesis of Alzheimer’s disease as well as to elimination of toxic amyloid from the brain by immunotherapy. Several BBB transporters have been implicated in Aβ exchange between brain parenchyma a...

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Detalles Bibliográficos
Autores principales: Zhang, Wandong, Xiong, Huaqi, Callaghan, Debbie, Liu, Hong, Jones, Aimee, Pei, Ke, Fatehi, Dorothy, Brunette, Eric, Stanimirovic, Danica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601014/
https://www.ncbi.nlm.nih.gov/pubmed/23432917
http://dx.doi.org/10.1186/2045-8118-10-13

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