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Antitumor activity of dichloroacetate on C6 glioma cell: in vitro and in vivo evaluation

Dichloroacetate (DCA), a small molecule mitochondria-targeting agent, can penetrate the blood–brain barrier, showing potential therapeutic effects on brain tumors. Considering the effects of DCA on tumor cellular metabolism, penetrating across the blood–brain barrier, as well as having potential ant...

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Detalles Bibliográficos
Autores principales: Duan, Yu, Zhao, Xin, Ren, Wei, Wang, Xin, Yu, Ke-Fu, Li, Dan, Zhang, Xuan, Zhang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601023/
https://www.ncbi.nlm.nih.gov/pubmed/23515860
http://dx.doi.org/10.2147/OTT.S40992

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