Anti-Allergic Cromones Inhibit Histamine and Eicosanoid Release from Activated Human and Murine Mast Cells by Releasing Annexin A1

BACKGROUND AND PURPOSE: Although the ‘cromones’ (di-sodium cromoglycate and sodium nedocromil) are used to treat allergy and asthma, their ‘mast cell stabilising’ mechanism of pharmacological action has never been convincingly explained. Here, we investigate the hypothesis that these drugs act by st...

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Detalles Bibliográficos
Autores principales: Yazid, Samia, Sinniah, Ajantha, Solito, Egle, Calder, Virginia, Flower, Rod J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601088/
https://www.ncbi.nlm.nih.gov/pubmed/23527056
http://dx.doi.org/10.1371/journal.pone.0058963

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601088/
https://www.ncbi.nlm.nih.gov/pubmed/23527056
http://dx.doi.org/10.1371/journal.pone.0058963

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