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Direct Transformation of Lung Microenvironment by Interferon-α Treatment Counteracts Growth of Lung Metastasis of Hepatocellular Carcinoma

BACKGROUND: Interferon (IFN)-α is effective in inhibiting tumor growth and metastasis of hepatocellular carcinoma (HCC). However, the biologic mechanisms of IFN-α treatment in lung metastasis are not yet clear. METHODS: The effect of IFN-α treatment was studied by using an orthotopic xenograft model...

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Detalles Bibliográficos
Autores principales: Zhuang, Peng-Yuan, Shen, Jun, Zhu, Xiao-Dong, Zhang, Ju-Bo, Tang, Zhao-You, Qin, Lun-Xiu, Sun, Hui-Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601095/
https://www.ncbi.nlm.nih.gov/pubmed/23527047
http://dx.doi.org/10.1371/journal.pone.0058913