Neutrophil extracellular traps: A new link to cancer-associated thrombosis and potential implications for tumor progression

Cancers prime neutrophils to release extracellular DNA traps through the systemic release of granulocyte colony-stimulating factor (G-CSF). We recently showed that these circulating neutrophil extracellular traps (NETs) promote the establishment of a pro-thrombotic state. The role of NETs in cancer...

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Detalles Bibliográficos
Autores principales: Demers, Mélanie, Wagner, Denisa D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601165/
https://www.ncbi.nlm.nih.gov/pubmed/23526174
http://dx.doi.org/10.4161/onci.22946
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author Demers, Mélanie
Wagner, Denisa D.
author_facet Demers, Mélanie
Wagner, Denisa D.
author_sort Demers, Mélanie
collection PubMed
description Cancers prime neutrophils to release extracellular DNA traps through the systemic release of granulocyte colony-stimulating factor (G-CSF). We recently showed that these circulating neutrophil extracellular traps (NETs) promote the establishment of a pro-thrombotic state. The role of NETs in cancer biology and tumor progression may prove much more than an unfortunate side effect of cancer.
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spelling pubmed-36011652013-03-22 Neutrophil extracellular traps: A new link to cancer-associated thrombosis and potential implications for tumor progression Demers, Mélanie Wagner, Denisa D. Oncoimmunology Author's View Cancers prime neutrophils to release extracellular DNA traps through the systemic release of granulocyte colony-stimulating factor (G-CSF). We recently showed that these circulating neutrophil extracellular traps (NETs) promote the establishment of a pro-thrombotic state. The role of NETs in cancer biology and tumor progression may prove much more than an unfortunate side effect of cancer. Landes Bioscience 2013-02-01 /pmc/articles/PMC3601165/ /pubmed/23526174 http://dx.doi.org/10.4161/onci.22946 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Demers, Mélanie
Wagner, Denisa D.
Neutrophil extracellular traps: A new link to cancer-associated thrombosis and potential implications for tumor progression
title Neutrophil extracellular traps: A new link to cancer-associated thrombosis and potential implications for tumor progression
title_full Neutrophil extracellular traps: A new link to cancer-associated thrombosis and potential implications for tumor progression
title_fullStr Neutrophil extracellular traps: A new link to cancer-associated thrombosis and potential implications for tumor progression
title_full_unstemmed Neutrophil extracellular traps: A new link to cancer-associated thrombosis and potential implications for tumor progression
title_short Neutrophil extracellular traps: A new link to cancer-associated thrombosis and potential implications for tumor progression
title_sort neutrophil extracellular traps: a new link to cancer-associated thrombosis and potential implications for tumor progression
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601165/
https://www.ncbi.nlm.nih.gov/pubmed/23526174
http://dx.doi.org/10.4161/onci.22946
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