Retinoic acid-producing DCs and gut-tropic FOXP3(+) regulatory T cells in the induction of oral tolerance

The systemic unresponsiveness of the immune system to orally administered antigens is known as oral tolerance. Recent findings describe a new step for the induction of oral tolerance, consisting in the homing of FOXP3(+) regulatory T cells to the small bowel and the local acquisition of full immunos...

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Detalles Bibliográficos
Autor principal: Villablanca, Eduardo J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601169/
https://www.ncbi.nlm.nih.gov/pubmed/23526672
http://dx.doi.org/10.4161/onci.22987
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author Villablanca, Eduardo J.
author_facet Villablanca, Eduardo J.
author_sort Villablanca, Eduardo J.
collection PubMed
description The systemic unresponsiveness of the immune system to orally administered antigens is known as oral tolerance. Recent findings describe a new step for the induction of oral tolerance, consisting in the homing of FOXP3(+) regulatory T cells to the small bowel and the local acquisition of full immunosuppressive capacities, a process in which retinoic acid-producing dendritic cells might play a crucial role.
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spelling pubmed-36011692013-03-22 Retinoic acid-producing DCs and gut-tropic FOXP3(+) regulatory T cells in the induction of oral tolerance Villablanca, Eduardo J. Oncoimmunology Author's View The systemic unresponsiveness of the immune system to orally administered antigens is known as oral tolerance. Recent findings describe a new step for the induction of oral tolerance, consisting in the homing of FOXP3(+) regulatory T cells to the small bowel and the local acquisition of full immunosuppressive capacities, a process in which retinoic acid-producing dendritic cells might play a crucial role. Landes Bioscience 2013-02-01 /pmc/articles/PMC3601169/ /pubmed/23526672 http://dx.doi.org/10.4161/onci.22987 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Villablanca, Eduardo J.
Retinoic acid-producing DCs and gut-tropic FOXP3(+) regulatory T cells in the induction of oral tolerance
title Retinoic acid-producing DCs and gut-tropic FOXP3(+) regulatory T cells in the induction of oral tolerance
title_full Retinoic acid-producing DCs and gut-tropic FOXP3(+) regulatory T cells in the induction of oral tolerance
title_fullStr Retinoic acid-producing DCs and gut-tropic FOXP3(+) regulatory T cells in the induction of oral tolerance
title_full_unstemmed Retinoic acid-producing DCs and gut-tropic FOXP3(+) regulatory T cells in the induction of oral tolerance
title_short Retinoic acid-producing DCs and gut-tropic FOXP3(+) regulatory T cells in the induction of oral tolerance
title_sort retinoic acid-producing dcs and gut-tropic foxp3(+) regulatory t cells in the induction of oral tolerance
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601169/
https://www.ncbi.nlm.nih.gov/pubmed/23526672
http://dx.doi.org/10.4161/onci.22987
work_keys_str_mv AT villablancaeduardoj retinoicacidproducingdcsandguttropicfoxp3regulatorytcellsintheinductionoforaltolerance

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