Neuropilin 1 guides regulatory T cells into VEGF-producing melanoma

Regulatory T cells (Tregs) interfere with antitumor immune responses, hence facilitating oncogenesis and tumor progression. Our recent findings indicate that neuropilin 1, which is highly expressed by Tregs, mediates the infiltration of these cells into the tumor in a vascular endothelial growth fac...

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Detalles Bibliográficos
Autor principal: Hansen, Wiebke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601175/
https://www.ncbi.nlm.nih.gov/pubmed/23524975
http://dx.doi.org/10.4161/onci.23039
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author Hansen, Wiebke
author_facet Hansen, Wiebke
author_sort Hansen, Wiebke
collection PubMed
description Regulatory T cells (Tregs) interfere with antitumor immune responses, hence facilitating oncogenesis and tumor progression. Our recent findings indicate that neuropilin 1, which is highly expressed by Tregs, mediates the infiltration of these cells into the tumor in a vascular endothelial growth factor (VEGF)-dependent manner, thereby contributing to cancer-associated immunosuppression.
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spelling pubmed-36011752013-03-22 Neuropilin 1 guides regulatory T cells into VEGF-producing melanoma Hansen, Wiebke Oncoimmunology Author's View Regulatory T cells (Tregs) interfere with antitumor immune responses, hence facilitating oncogenesis and tumor progression. Our recent findings indicate that neuropilin 1, which is highly expressed by Tregs, mediates the infiltration of these cells into the tumor in a vascular endothelial growth factor (VEGF)-dependent manner, thereby contributing to cancer-associated immunosuppression. Landes Bioscience 2013-02-01 /pmc/articles/PMC3601175/ /pubmed/23524975 http://dx.doi.org/10.4161/onci.23039 Text en Copyright © Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Hansen, Wiebke
Neuropilin 1 guides regulatory T cells into VEGF-producing melanoma
title Neuropilin 1 guides regulatory T cells into VEGF-producing melanoma
title_full Neuropilin 1 guides regulatory T cells into VEGF-producing melanoma
title_fullStr Neuropilin 1 guides regulatory T cells into VEGF-producing melanoma
title_full_unstemmed Neuropilin 1 guides regulatory T cells into VEGF-producing melanoma
title_short Neuropilin 1 guides regulatory T cells into VEGF-producing melanoma
title_sort neuropilin 1 guides regulatory t cells into vegf-producing melanoma
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601175/
https://www.ncbi.nlm.nih.gov/pubmed/23524975
http://dx.doi.org/10.4161/onci.23039
work_keys_str_mv AT hansenwiebke neuropilin1guidesregulatorytcellsintovegfproducingmelanoma

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