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Glycan-based DC-SIGN targeting to enhance antigen cross-presentation in anticancer vaccines

In vivo dendritic-cell targeting constitutes a promising strategy for anticancer vaccination. Here, we discuss the usage of multivalent DC-SIGN-targeting glycan platforms that allow for the efficient routing of antigens to the endo-lysosomal pathway as well as to a yet uncharacterized cross-presenta...

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Detalles Bibliográficos
Autores principales:	García-Vallejo, Juan J., Unger, Wendy W. J., Kalay, Hakan, van Kooyk, Yvette
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2013
Materias:	Author's View
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601176/ https://www.ncbi.nlm.nih.gov/pubmed/23525136 http://dx.doi.org/10.4161/onci.23040

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