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Targeting SIRPα in cancer
Strategies to harness the patient’s immune system to fight cancer have mainly involved adoptive T-cell transfer. We and others have recently highlighted an alternative immunotherapeutic approach to cancer that consists of enhancing the macrophage-mediated clearance of leukemia cells through the bloc...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Landes Bioscience
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601179/ https://www.ncbi.nlm.nih.gov/pubmed/23525504 http://dx.doi.org/10.4161/onci.23081 |
| _version_ | 1782475731351109632 |
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| author | Ho, Jenny M. Danska, Jayne S. Wang, Jean C.Y. |
| author_facet | Ho, Jenny M. Danska, Jayne S. Wang, Jean C.Y. |
| author_sort | Ho, Jenny M. |
| collection | PubMed |
| description | Strategies to harness the patient’s immune system to fight cancer have mainly involved adoptive T-cell transfer. We and others have recently highlighted an alternative immunotherapeutic approach to cancer that consists of enhancing the macrophage-mediated clearance of leukemia cells through the blockade of inhibitory signals transmitted by signal regulatory protein α (SIRPα). |
| format | Online Article Text |
| id | pubmed-3601179 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2013 |
| publisher | Landes Bioscience |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-36011792013-03-22 Targeting SIRPα in cancer Ho, Jenny M. Danska, Jayne S. Wang, Jean C.Y. Oncoimmunology Author's View Strategies to harness the patient’s immune system to fight cancer have mainly involved adoptive T-cell transfer. We and others have recently highlighted an alternative immunotherapeutic approach to cancer that consists of enhancing the macrophage-mediated clearance of leukemia cells through the blockade of inhibitory signals transmitted by signal regulatory protein α (SIRPα). Landes Bioscience 2013-02-01 /pmc/articles/PMC3601179/ /pubmed/23525504 http://dx.doi.org/10.4161/onci.23081 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited. |
| spellingShingle | Author's View Ho, Jenny M. Danska, Jayne S. Wang, Jean C.Y. Targeting SIRPα in cancer |
| title | Targeting SIRPα in cancer |
| title_full | Targeting SIRPα in cancer |
| title_fullStr | Targeting SIRPα in cancer |
| title_full_unstemmed | Targeting SIRPα in cancer |
| title_short | Targeting SIRPα in cancer |
| title_sort | targeting sirpα in cancer |
| topic | Author's View |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601179/ https://www.ncbi.nlm.nih.gov/pubmed/23525504 http://dx.doi.org/10.4161/onci.23081 |
| work_keys_str_mv | AT hojennym targetingsirpaincancer AT danskajaynes targetingsirpaincancer AT wangjeancy targetingsirpaincancer |