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An Endogenous Vitamin K-Dependent Mechanism Regulates Cell Proliferation in the Brain Subventricular Stem Cell Niche

Neural stem cells (NSC) persist in the adult mammalian brain, within the subventricular zone (SVZ). The endogenous mechanisms underpinning SVZ stem and progenitor cell proliferation are not fully elucidated. Vitamin K-dependent proteins (VKDPs) are mainly secreted factors that were initially discove...

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Detalles Bibliográficos
Autores principales: Gely-Pernot, Aurore, Coronas, Valérie, Harnois, Thomas, Prestoz, Laetitia, Mandairon, Nathalie, Didier, Anne, Berjeaud, Jean Marc, Monvoisin, Arnaud, Bourmeyster, Nicolas, De Frutos, Pablo García, Philippe, Michel, Benzakour, Omar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601423/
https://www.ncbi.nlm.nih.gov/pubmed/22290807
http://dx.doi.org/10.1002/stem.1045