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Expression of functionally active sialylated human erythropoietin in plants

Recombinant human erythropoietin (rhEPO), a glycohormone, is one of the leading biopharmaceutical products. The production of rhEPO is currently restricted to mammalian cell expression systems because of rhEPO's highly complex glycosylation pattern, which is a major determinant for drug-efficac...

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Detalles Bibliográficos
Autores principales:	Jez, Jakub, Castilho, Alexandra, Grass, Josephine, Vorauer-Uhl, Karola, Sterovsky, Thomas, Altmann, Friedrich, Steinkellner, Herta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	WILEY-VCH Verlag 2013
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601435/ https://www.ncbi.nlm.nih.gov/pubmed/23325672 http://dx.doi.org/10.1002/biot.201200363

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