How to draw the line in biomedical research

The use of the least squares method to calculate the best-fitting line through a two-dimensional scatter plot typically requires the user to assume that one of the variables depends on the other. However, in many cases the relationship between the two variables is more complex, and it is not valid t...

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Detalles Bibliográficos
Autores principales: Huang, Lisa, Rattner, Amir, Liu, Han, Nathans, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Feature Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601633/
https://www.ncbi.nlm.nih.gov/pubmed/23538852
http://dx.doi.org/10.7554/eLife.00638
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author Huang, Lisa
Rattner, Amir
Liu, Han
Nathans, Jeremy
author_facet Huang, Lisa
Rattner, Amir
Liu, Han
Nathans, Jeremy
author_sort Huang, Lisa
collection PubMed
description The use of the least squares method to calculate the best-fitting line through a two-dimensional scatter plot typically requires the user to assume that one of the variables depends on the other. However, in many cases the relationship between the two variables is more complex, and it is not valid to say that one variable is independent and the other is dependent. When analysing such data researchers should consider plotting the three regression lines that can be calculated for any two-dimensional scatter plot.
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spelling pubmed-36016332013-03-28 How to draw the line in biomedical research Huang, Lisa Rattner, Amir Liu, Han Nathans, Jeremy eLife Feature Article The use of the least squares method to calculate the best-fitting line through a two-dimensional scatter plot typically requires the user to assume that one of the variables depends on the other. However, in many cases the relationship between the two variables is more complex, and it is not valid to say that one variable is independent and the other is dependent. When analysing such data researchers should consider plotting the three regression lines that can be calculated for any two-dimensional scatter plot. eLife Sciences Publications, Ltd 2013-03-19 /pmc/articles/PMC3601633/ /pubmed/23538852 http://dx.doi.org/10.7554/eLife.00638 Text en © 2013, Huang et al http://creativecommons.org/licenses/by/3.0/ This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Feature Article
Huang, Lisa
Rattner, Amir
Liu, Han
Nathans, Jeremy
How to draw the line in biomedical research
title How to draw the line in biomedical research
title_full How to draw the line in biomedical research
title_fullStr How to draw the line in biomedical research
title_full_unstemmed How to draw the line in biomedical research
title_short How to draw the line in biomedical research
title_sort how to draw the line in biomedical research
topic Feature Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601633/
https://www.ncbi.nlm.nih.gov/pubmed/23538852
http://dx.doi.org/10.7554/eLife.00638
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