Cargando…
An evidence-based review of obatoclax mesylate in the treatment of hematological malignancies
Obatoclax mesylate is an intravenously-administered drug under investigation in Phase I and II clinical trials as a novel anticancer therapeutic for hematological malignancies and solid tumors. Obatoclax was developed as a pan-inhibitor of antiapoptotic members of the B cell chronic lymphocytic leuk...
Autores principales: | Goard, Carolyn A, Schimmer, Aaron D |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601645/ https://www.ncbi.nlm.nih.gov/pubmed/23515850 http://dx.doi.org/10.2147/CE.S42568 |
Ejemplares similares
-
A Multicenter Phase I/II Study of Obatoclax Mesylate Administered as a 3- or 24-Hour Infusion in Older Patients with Previously Untreated Acute Myeloid Leukemia
por: Schimmer, Aaron D., et al.
Publicado: (2014) -
Targeting nuclear import and export in hematological malignancies
por: Nachmias, Boaz, et al.
Publicado: (2020) -
Applying CRISPR-Cas9 screens to dissect hematological malignancies
por: Iyer, Deepak Narayanan, et al.
Publicado: (2022) -
The BH3 Mimetic Obatoclax Accumulates in Lysosomes and Causes Their Alkalinization
por: Stamelos, Vasileios A., et al.
Publicado: (2016) -
Apatinib mesylate tablet in the treatment of advanced malignant melanoma
por: Yang, Lingge, et al.
Publicado: (2018)