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Duration of rise in free fatty acids determines salicylate's effect on hepatic insulin sensitivity
We have shown in rats that sodium salicylate (SS), which inhibits IkBa kinase B (IKKB), prevents hepatic and peripheral insulin resistance caused by short-term (7 h) i.v. administration of Intralipid and heparin (IH). We wished to further determine whether this beneficial effect of SS persisted afte...
Autores principales: | Pereira, Sandra, Yu, Wen Qin, Frigolet, María E, Beaudry, Jacqueline L, Shpilberg, Yaniv, Park, Edward, Dirlea, Cristina, Nyomba, B L Grégoire, Riddell, Michael C, Fantus, I George, Giacca, Adria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioScientifica
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601809/ https://www.ncbi.nlm.nih.gov/pubmed/23328071 http://dx.doi.org/10.1530/JOE-12-0214 |
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