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Metabolic syndrome risk factors in overweight, obese, and extremely obese brazilian adolescents

BACKGROUND: Obesity in infancy and adolescence has acquired epidemic dimensions worldwide and is considered a risk factor for a number of disorders that can manifest at an early age, such as Metabolic Syndrome (MS). In this study, we evaluated overweight, obese, and extremely obese adolescents for t...

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Autores principales: Rizzo, Anapaula CB, Goldberg, Tamara BL, Silva, Carla C, Kurokawa, Cilmery S, Nunes, Helio RC, Corrente, José E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602008/
https://www.ncbi.nlm.nih.gov/pubmed/23363783
http://dx.doi.org/10.1186/1475-2891-12-19
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author Rizzo, Anapaula CB
Goldberg, Tamara BL
Silva, Carla C
Kurokawa, Cilmery S
Nunes, Helio RC
Corrente, José E
author_facet Rizzo, Anapaula CB
Goldberg, Tamara BL
Silva, Carla C
Kurokawa, Cilmery S
Nunes, Helio RC
Corrente, José E
author_sort Rizzo, Anapaula CB
collection PubMed
description BACKGROUND: Obesity in infancy and adolescence has acquired epidemic dimensions worldwide and is considered a risk factor for a number of disorders that can manifest at an early age, such as Metabolic Syndrome (MS). In this study, we evaluated overweight, obese, and extremely obese adolescents for the presence of MS, and studied the prevalence of single factors of the syndrome in this population. METHODS: A total of 321 adolescents (174 females and 147 males) aged 10 to 16 years, attending the Adolescent Outpatient Clinic of Botucatu School of Medicine, Brazil, between April 2009 and April 2011 were enrolled in this study. Adolescents underwent anthropometric evaluation (weight, height, and abdominal circumference) and Body Mass Index (BMI) was estimated according to age and gender, following Disease Control and Prevention Centers recommendations (CDC, 2000). Blood pressure was measured and individuals with BMI ≥ 85(th) percentile were submitted to laboratory evaluation for Total Cholesterol, HDL and LDL Cholesterol, Triglycerides, Fasting Insulinemia, and Fasting Glycemia to identify MS factors, according to the criteria suggested by the International Diabetes Federation. Insulin resistance was calculated by HOMA-IR, Quicki, and Fasting Glycemia/Fasting Insulinemia (FGI). RESULTS AND DISCUSSION: Of the 321 adolescents, 95 (29.6%) were overweight, 129 (40.2%) were obese, and 97 (30.2%) were extremely obese. Around 18% were diagnosed with MS. The most prevalent risk factors were abdominal circumference ≥90(th) percentile (55%), HDL < 40 mg/dL (35.5%), High Pressure ≥130/85 mm/Hg (21%), Triglycerides ≥150 mg/dL (18.5%), and Fasting Glycemia ≥100 mg/dL (2%). Insulin resistance was observed in 65% of the adolescents. CONCLUSION: An increased prevalence of overweight and obesity, together with cardiometabolic risk factors such as dyslipidemia and abnormal blood pressure, were observed in adolescents, contributing to the onset of metabolic syndrome at younger ages. Risk factors for MS were more prevalent in females.
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spelling pubmed-36020082013-03-20 Metabolic syndrome risk factors in overweight, obese, and extremely obese brazilian adolescents Rizzo, Anapaula CB Goldberg, Tamara BL Silva, Carla C Kurokawa, Cilmery S Nunes, Helio RC Corrente, José E Nutr J Research BACKGROUND: Obesity in infancy and adolescence has acquired epidemic dimensions worldwide and is considered a risk factor for a number of disorders that can manifest at an early age, such as Metabolic Syndrome (MS). In this study, we evaluated overweight, obese, and extremely obese adolescents for the presence of MS, and studied the prevalence of single factors of the syndrome in this population. METHODS: A total of 321 adolescents (174 females and 147 males) aged 10 to 16 years, attending the Adolescent Outpatient Clinic of Botucatu School of Medicine, Brazil, between April 2009 and April 2011 were enrolled in this study. Adolescents underwent anthropometric evaluation (weight, height, and abdominal circumference) and Body Mass Index (BMI) was estimated according to age and gender, following Disease Control and Prevention Centers recommendations (CDC, 2000). Blood pressure was measured and individuals with BMI ≥ 85(th) percentile were submitted to laboratory evaluation for Total Cholesterol, HDL and LDL Cholesterol, Triglycerides, Fasting Insulinemia, and Fasting Glycemia to identify MS factors, according to the criteria suggested by the International Diabetes Federation. Insulin resistance was calculated by HOMA-IR, Quicki, and Fasting Glycemia/Fasting Insulinemia (FGI). RESULTS AND DISCUSSION: Of the 321 adolescents, 95 (29.6%) were overweight, 129 (40.2%) were obese, and 97 (30.2%) were extremely obese. Around 18% were diagnosed with MS. The most prevalent risk factors were abdominal circumference ≥90(th) percentile (55%), HDL < 40 mg/dL (35.5%), High Pressure ≥130/85 mm/Hg (21%), Triglycerides ≥150 mg/dL (18.5%), and Fasting Glycemia ≥100 mg/dL (2%). Insulin resistance was observed in 65% of the adolescents. CONCLUSION: An increased prevalence of overweight and obesity, together with cardiometabolic risk factors such as dyslipidemia and abnormal blood pressure, were observed in adolescents, contributing to the onset of metabolic syndrome at younger ages. Risk factors for MS were more prevalent in females. BioMed Central 2013-01-30 /pmc/articles/PMC3602008/ /pubmed/23363783 http://dx.doi.org/10.1186/1475-2891-12-19 Text en Copyright ©2013 Rizzo et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Rizzo, Anapaula CB
Goldberg, Tamara BL
Silva, Carla C
Kurokawa, Cilmery S
Nunes, Helio RC
Corrente, José E
Metabolic syndrome risk factors in overweight, obese, and extremely obese brazilian adolescents
title Metabolic syndrome risk factors in overweight, obese, and extremely obese brazilian adolescents
title_full Metabolic syndrome risk factors in overweight, obese, and extremely obese brazilian adolescents
title_fullStr Metabolic syndrome risk factors in overweight, obese, and extremely obese brazilian adolescents
title_full_unstemmed Metabolic syndrome risk factors in overweight, obese, and extremely obese brazilian adolescents
title_short Metabolic syndrome risk factors in overweight, obese, and extremely obese brazilian adolescents
title_sort metabolic syndrome risk factors in overweight, obese, and extremely obese brazilian adolescents
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602008/
https://www.ncbi.nlm.nih.gov/pubmed/23363783
http://dx.doi.org/10.1186/1475-2891-12-19
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