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Combined analysis of circulating β-endorphin with gene polymorphisms in OPRM1, CACNAD2 and ABCB1 reveals correlation with pain, opioid sensitivity and opioid-related side effects

BACKGROUND: Opioids are associated with wide inter-individual variability in the analgesic response and a narrow therapeutic index. This may be partly explained by the presence of single nucleotide polymorphisms (SNPs) in genes encoding molecular entities involved in opioid metabolism and receptor a...

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Detalles Bibliográficos
Autores principales:	Rhodin, Annica, Grönbladh, Alfhild, Ginya, Harumi, Nilsson, Kent W, Rosenblad, Andreas, Zhou, Qin, Enlund, Mats, Hallberg, Mathias, Gordh, Torsten, Nyberg, Fred
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602034/ https://www.ncbi.nlm.nih.gov/pubmed/23402298 http://dx.doi.org/10.1186/1756-6606-6-8

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