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Comparative analysis of the transduction efficiency of five adeno associated virus serotypes and VSV-G pseudotype lentiviral vector in lung cancer cells
BACKGROUND: Lung cancer is the leading cause of cancer-related deaths in the US. Recombinant vectors based on adeno-associated virus (AAV) and lentivirus are promising delivery tools for gene therapy due to low toxicity and long term expression. The efficiency of the gene delivery system is one of t...
Autores principales: | Chen, Chiachen, Akerstrom, Victoria, Baus, James, Lan, Michael S, Breslin, Mary B |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602085/ https://www.ncbi.nlm.nih.gov/pubmed/23497017 http://dx.doi.org/10.1186/1743-422X-10-86 |
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