An Amphipathic Alpha-Helix in the Prodomain of Cocaine and Amphetamine Regulated Transcript Peptide Precursor Serves as Its Sorting Signal to the Regulated Secretory Pathway

Cocaine and Amphetamine Regulated Transcript (CART) peptides are anorexigenic neuropeptides. The L34F mutation in human CART peptide precursor (proCART) has been linked to obesity (Yanik et al. Endocrinology 147: 39, 2006). Decrease in CART peptide levels in individuals carrying the L34F mutation wa...

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Detalles Bibliográficos
Autores principales: Blanco, Elías H., Lagos, Carlos F., Andrés, María Estela, Gysling, Katia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602189/
https://www.ncbi.nlm.nih.gov/pubmed/23527253
http://dx.doi.org/10.1371/journal.pone.0059695

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602189/
https://www.ncbi.nlm.nih.gov/pubmed/23527253
http://dx.doi.org/10.1371/journal.pone.0059695

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