Cargando…

An Amphipathic Alpha-Helix in the Prodomain of Cocaine and Amphetamine Regulated Transcript Peptide Precursor Serves as Its Sorting Signal to the Regulated Secretory Pathway

Cocaine and Amphetamine Regulated Transcript (CART) peptides are anorexigenic neuropeptides. The L34F mutation in human CART peptide precursor (proCART) has been linked to obesity (Yanik et al. Endocrinology 147: 39, 2006). Decrease in CART peptide levels in individuals carrying the L34F mutation wa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Blanco, Elías H., Lagos, Carlos F., Andrés, María Estela, Gysling, Katia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602189/ https://www.ncbi.nlm.nih.gov/pubmed/23527253 http://dx.doi.org/10.1371/journal.pone.0059695

Ejemplares similares

A transient amphipathic helix in the prodomain of PCSK9 facilitates binding to low-density lipoprotein particles
por: Sarkar, Samantha K., et al.
Publicado: (2020)

Lipid Binding of the Amphipathic Helix Serving as Membrane Anchor of Pestivirus Glycoprotein E(rns)
por: Aberle, Daniel, et al.
Publicado: (2015)

Neutral lipids regulate amphipathic helix affinity for model lipid droplets
por: Chorlay, Aymeric, et al.
Publicado: (2020)

Cholesterol Binds the Amphipathic Helix of IFITM3 and Regulates Antiviral Activity
por: Rahman, Kazi, et al.
Publicado: (2022)

Cocaine-and Amphetamine Regulated Transcript (CART) Peptide Is Expressed in Precursor Cells and Somatotropes of the Mouse Pituitary Gland
por: Mortensen, Amanda H., et al.
Publicado: (2016)

Prediction of amphipathic helix—membrane interactions with Rosetta
por: Gulsevin, Alican, et al.
Publicado: (2021)

Expression of cocaine- and amphetamine-regulated transcript (CART) in hen ovary
por: Li, Pengfei, et al.
Publicado: (2017)

Coemergence of the Amphipathic Helix on Ameloblastin With Mammalian Prismatic Enamel
por: Su, Jingtan, et al.
Publicado: (2022)

The N–Terminal Tail of hERG Contains an Amphipathic α–Helix That Regulates Channel Deactivation
por: Ng, Chai Ann, et al.
Publicado: (2011)

The molecular recognition of phosphatidic acid by an amphipathic helix in Opi1
por: Hofbauer, Harald F., et al.
Publicado: (2018)

An Amphipathic Alpha‐Helix Guides Maturation of the Ribosomally‐Synthesized Lipolanthines
por: Wiebach, Vincent, et al.
Publicado: (2020)

Cocaine- and Amphetamine-Regulated Transcript (CART) Signaling within the Paraventricular Thalamus Modulates Cocaine-Seeking Behaviour
por: James, Morgan H., et al.
Publicado: (2010)

Electrophysiological characteristics of paraventricular thalamic (PVT) neurons in response to cocaine and cocaine- and amphetamine-regulated transcript (CART)
por: Yeoh, Jiann Wei, et al.
Publicado: (2014)

Association of Leukocytosis with Amphetamine and Cocaine Use
por: Richards, John R., et al.
Publicado: (2014)

Blunted Vagal Cocaine- and Amphetamine-Regulated Transcript Promotes Hyperphagia and Weight Gain
por: Lee, Shin J., et al.
Publicado: (2020)

The Role of Cocaine- and Amphetamine-Regulated Transcript (CART) in Cancer: A Systematic Review
por: Owe-Larsson, Maja, et al.
Publicado: (2023)

Expression and role of cocaine-amphetamine regulated transcript (CART) in the proliferation of biliary epithelium
por: Casini, Arianna, et al.
Publicado: (2023)

An amphipathic helix enables septins to sense micrometer-scale membrane curvature
por: Cannon, Kevin S., et al.
Publicado: (2019)

Protein Amphipathic Helix Insertion: A Mechanism to Induce Membrane Fission
por: Zhukovsky, Mikhail A., et al.
Publicado: (2019)

The prodomain of caspase-3 regulates its own removal and caspase activation
por: Ponder, Katelyn G., et al.
Publicado: (2019)

Regulation of Pituitary Cocaine- and Amphetamine-Regulated Transcript Expression and Secretion by Hypothalamic Gonadotropin-Releasing Hormone in Chickens
por: Mo, Chunheng, et al.
Publicado: (2019)

Colocalization of Cocaine- and Amphetamine-Regulated Transcript with Kisspeptin and Neurokinin B in the Human Infundibular Region
por: Skrapits, Katalin, et al.
Publicado: (2014)

Cocaine- and amphetamine-regulated transcript (CART) is associated with dopamine and is protective against ischemic stroke
por: Lin, Lili, et al.
Publicado: (2018)

Essential Mycoplasma Glycolipid Synthase Adheres to the Cell Membrane by Means of an Amphipathic Helix
por: Romero-García, Javier, et al.
Publicado: (2019)

An amphipathic helix in Brl1 is required for nuclear pore complex biogenesis in S. cerevisiae
por: Kralt, Annemarie, et al.
Publicado: (2022)

Synergistic effect of CART (cocaine- and amphetamine-regulated transcript) peptide and cholecystokinin on food intake regulation in lean mice
por: Maletínská, Lenka, et al.
Publicado: (2008)

Levels of Cocaine- and Amphetamine-Regulated Transcript in Vagal Afferents in the Mouse Are Unaltered in Response to Metabolic Challenges
por: Yuan, Xuefeng, et al.
Publicado: (2016)

Cocaine- and Amphetamine-Regulated Transcript (CART) Peptide Plays Critical Role in Psychostimulant-Induced Depression
por: Meng, Qing, et al.
Publicado: (2018)

Cell-free protein sorting to the regulated and constitutive secretory pathways
por: Tooze, Sharon A., et al.
Publicado: (1990)

Glycogen Synthase Kinase 3β Is a Key Regulator in the Inhibitory Effects of Accumbal Cocaine- and Amphetamine-Regulated Transcript Peptide 55–102 on Amphetamine-Induced Locomotor Activity
por: Cho, Bo Ram, et al.
Publicado: (2022)

Cocaine and amphetamine-like psychostimulants: neurocircuitry and glutamate neuroplasticity
por: Kalivas, Peter W.
Publicado: (2007)

Pneumomediastinum and subcutaneous emphysema post cocaine and amphetamine insufflation
por: Hawkins, Leah, et al.
Publicado: (2022)

Role of Amphipathic Helix of a Herpesviral Protein in Membrane Deformation and T Cell Receptor Downregulation
por: Min, Chan-Ki, et al.
Publicado: (2008)

A giant amphipathic helix from a perilipin that is adapted for coating lipid droplets
por: Čopič, Alenka, et al.
Publicado: (2018)

Membrane remodeling by the M2 amphipathic helix drives influenza virus membrane scission
por: Martyna, Agnieszka, et al.
Publicado: (2017)

An amphipathic α-helix directs palmitoylation of the large intracellular loop of the sodium/calcium exchanger
por: Plain, Fiona, et al.
Publicado: (2017)

Cholesterol Alters the Orientation and Activity of the Influenza Virus M2 Amphipathic Helix in the Membrane
por: Martyna, Agnieszka, et al.
Publicado: (2020)

A conserved viral amphipathic helix governs the replication site-specific membrane association
por: Sathanantham, Preethi, et al.
Publicado: (2022)

A perinuclear α-helix with amphipathic features in Brl1 promotes NPC assembly
por: Vitale, Jlenia, et al.
Publicado: (2022)

An inducible amphipathic α-helix mediates subcellular targeting and membrane binding of RPE65
por: Uppal, Sheetal, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_jik24kbv4j10j6imcclsb9kp75