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RNA-Dependent Protein Kinase Is Essential for 2-Methoxyestradiol-Induced Autophagy in Osteosarcoma Cells

Osteosarcoma is the most common primary malignant bone tumor in children and young adults. Surgical resection and adjunctive chemotherapy are the only widely available options of treatment for this disease. Anti-tumor compound 2-Methoxyestradiol (2-ME) triggers cell death through the induction of ap...

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Detalles Bibliográficos
Autores principales:	Yang, Caihong, Shogren, Kristen L., Goyal, Ribu, Bravo, Dalibel, Yaszemski, Michael J., Maran, Avudaiappan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602192/ https://www.ncbi.nlm.nih.gov/pubmed/23527187 http://dx.doi.org/10.1371/journal.pone.0059406

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