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Identification of a Missing Link in the Evolution of an Enzyme into a Transcriptional Regulator

The evolution of transcriptional regulators through the recruitment of DNA-binding domains by enzymes is a widely held notion. However, few experimental approaches have directly addressed this hypothesis. Here we report the reconstruction of a plausible pathway for the evolution of an enzyme into a...

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Detalles Bibliográficos
Autores principales:	Durante-Rodríguez, Gonzalo, Mancheño, José Miguel, Rivas, Germán, Alfonso, Carlos, García, José Luis, Díaz, Eduardo, Carmona, Manuel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602430/ https://www.ncbi.nlm.nih.gov/pubmed/23526945 http://dx.doi.org/10.1371/journal.pone.0057518

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